ccmC protein (Anaplasma marginale) - STRING interaction network

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ccmC

Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (250 aa)

Predicted Functional Partners:

ccmB

0.998

ccmE

0.993

ccmA

0.989

dsbE

0.928

ccmF

0.904

AMF_482

0.859

ruvA

0.829

ruvB

0.802

hemD

0.621

dnaA

0.527

Your Current Organism:

Anaplasma marginale

NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMF_482	ccmA	AMF_482	AMF_105	Conserved hypothetical protein; Possible subunit of a heme lyase.	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.621
AMF_482	ccmB	AMF_482	AMF_851	Conserved hypothetical protein; Possible subunit of a heme lyase.	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	0.554
AMF_482	ccmC	AMF_482	AMF_131	Conserved hypothetical protein; Possible subunit of a heme lyase.	Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.	0.859
AMF_482	ccmE	AMF_482	AMF_330	Conserved hypothetical protein; Possible subunit of a heme lyase.	Cytochrome c-type biogenesis protein (ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.895
AMF_482	ccmF	AMF_482	AMF_882	Conserved hypothetical protein; Possible subunit of a heme lyase.	Cytochrome c-type biogenesis protein (ccmF); Psort: bacterial inner membrane --- Certainty= 0.529(Affirmative); COG1138 CcmF cytochrome c biogenesis factor.	0.924
AMF_482	dsbE	AMF_482	AMF_115	Conserved hypothetical protein; Possible subunit of a heme lyase.	Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.	0.904
ccmA	AMF_482	AMF_105	AMF_482	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Conserved hypothetical protein; Possible subunit of a heme lyase.	0.621
ccmA	ccmB	AMF_105	AMF_851	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	0.995
ccmA	ccmC	AMF_105	AMF_131	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.	0.989
ccmA	ccmE	AMF_105	AMF_330	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Cytochrome c-type biogenesis protein (ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.955
ccmA	ccmF	AMF_105	AMF_882	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Cytochrome c-type biogenesis protein (ccmF); Psort: bacterial inner membrane --- Certainty= 0.529(Affirmative); COG1138 CcmF cytochrome c biogenesis factor.	0.668
ccmA	dsbE	AMF_105	AMF_115	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.	0.767
ccmB	AMF_482	AMF_851	AMF_482	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Conserved hypothetical protein; Possible subunit of a heme lyase.	0.554
ccmB	ccmA	AMF_851	AMF_105	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.995
ccmB	ccmC	AMF_851	AMF_131	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.	0.998
ccmB	ccmE	AMF_851	AMF_330	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Cytochrome c-type biogenesis protein (ccmE); Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.980
ccmB	ccmF	AMF_851	AMF_882	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Cytochrome c-type biogenesis protein (ccmF); Psort: bacterial inner membrane --- Certainty= 0.529(Affirmative); COG1138 CcmF cytochrome c biogenesis factor.	0.848
ccmB	dsbE	AMF_851	AMF_115	Heme exporter protein B (ccmB); Psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component.	Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.	0.888
ccmC	AMF_482	AMF_131	AMF_482	Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.	Conserved hypothetical protein; Possible subunit of a heme lyase.	0.859
ccmC	ccmA	AMF_131	AMF_105	Cytochrome c-type biogenesis protein (ccmC); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.	Heme exporter protein (ccmA); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.989

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