STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsQCell division protein (ftsQ); Psort: bacterial cytoplasm --- Certainty= 0.174(Affirmative); COG1589 FtsQ cell division septal protein. (261 aa)    
Predicted Functional Partners:
AMF_444
Conserved family - Septum formation initiator; psort: bacterial inner membrane --- Certainty= 0.399(Affirmative).
 
 
 
 0.996
ddlB
D-alanine--D-alanine ligase (ddlB); Cell wall formation.
  
  
 0.981
ftsA
Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
 
 0.980
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.976
ftsW
Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 0.956
pbpA2
Penicillin-binding protein (pbpA2); Psort: bacterial inner membrane --- Certainty= 0.516(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.949
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.925
secY
Preprotein translocase secY subunit (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.922
pbpA1
Penicillin-binding protein (pbpA1); Psort: bacterial inner membrane --- Certainty= 0.348(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2.
  
 
 0.920
murC
UDP-N-acetylmuramate-alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.910
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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