Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
pstSPhosphate ABC transporter, periplasmic phosphate-binding protein; Psort: bacterial outer membrane --- Certainty= 0.239(Affirmative) bacterial periplasmic space --- Certainty= 0.239(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.984 Max cleavage site probability: 0.934 between pos. 20 and 21; COG0226 ABC-type phosphate transport system, periplasmic component. (338 aa)    
Predicted Functional Partners:
pstC
ABC-type phosphate transport system, permease component (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
pstA
Phosphate ABC transporter (pstA); Psort: bacterial inner membrane --- Certainty= 0.660(Affirmative); COG0581 PstA ABC-type phosphate transport system, permease component.
 
 0.999
pstB
Phosphate ABC transporter (pstB); Psort: bacterial cytoplasm --- Certainty= 0.075(Affirmative); COG1117 PstB ABC-type phosphate transport system, ATPase component; Belongs to the ABC transporter superfamily.
  
 0.995
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
       0.656
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.608
rpsU
30s ribosomal protein s21 (rpsU); Psort: bacterial cytoplasm --- Certainty= 0.289(Affirmative); COG0828 RpsU ribosomal protein S21.
     
 0.575
pheT
phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit.
  
    0.530
czcR
Transcriptional activator protein (czcR); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.501
sucD
succinyl-CoA ligase chain A (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.463
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
     
 0.463
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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