STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msp5Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27. (210 aa)    
Predicted Functional Partners:
coxW
Cytochrome C oxidase assembly protein (coxW); Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
 
 0.920
coxB
Cytochrome c oxidase subunit II (coxB); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 0.895
cox11
Cytochrome c oxidase assembly protein (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
 
 0.886
AMF_357
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins.
 
 
 0.855
dsbE
Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.
   
 
 0.687
AMF_629
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outside --- Certainty= 0.300(Affirmative); COG2867 Oligoketide cyclase/lipid transport protein.
   
 
  0.675
pstS
Phosphate ABC transporter, periplasmic phosphate-binding protein; Psort: bacterial outer membrane --- Certainty= 0.239(Affirmative) bacterial periplasmic space --- Certainty= 0.239(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.984 Max cleavage site probability: 0.934 between pos. 20 and 21; COG0226 ABC-type phosphate transport system, periplasmic component.
       0.656
surf1
Surfeit locus protein 1 (surf1); Psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein.
  
 
 0.622
msp4
Major surface protein 4 (msp4); Member of msp2 superfamily; psort: bacterial cytoplasm --- Certainty= 0.211(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.933 between pos. 29 and 30.
      
 0.547
ctaB
Cytochrome c oxidase assembly factor (ctaB); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
  
 0.545
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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