Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tolBTOLB protein precursor (tolB); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (441 aa)    
Predicted Functional Partners:
pal
Peptidoglycan-associated lipoprotein precursor; Psort: bacterial inner membrane --- Certainty= 0.291(Affirmative); COG2885 OmpA Outer membrane protein and related peptidoglycan-associated (lipo)proteins.
 
 
 0.937
tolQ
TOLQ protein (tolQ); Psort: bacterial inner membrane --- Certainty= 0.378(Affirmative); COG0811 TolQ biopolymer transport protein.
 
  
 0.872
tolR
TOLR protein (tolR); Psort: bacterial inner membrane --- Certainty= 0.537(Affirmative); COG0848 ExbD biopolymer transport protein.
 
  
 0.823
AMF_245
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.919(Affirmative).
 
 
 0.813
AMF_179
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.172(Affirmative); COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily.
       0.807
rlpA
Rare lipoprotein A precursor (rlpA); Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
 
 0.721
bamD
Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.676
oma87
Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.604
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
  
   
 0.541
AMF_180
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.486(Affirmative).
       0.500
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.