STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
aroA3-phosphoshikimate 1-carboxyvinyltransferase (aroA); Psort: bacterial inner membrane --- Certainty= 0.257(Affirmative); COG0128 AroA 5-enolpyruvylshikimate-3-phosphate synthase. (462 aa)    
Predicted Functional Partners:
dnaE
DNA polymerase III, alpha subunit (dnaE); Psort: bacterial inner membrane --- Certainty= 0.113(Affirmative); COG0587 DnaE DNA polymerase III alpha subunit.
     
 0.499
pheT
phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit.
  
  
 0.499
lysC
Aspartokinase (lysC); Psort: bacterial inner membrane --- Certainty= 0.183(Affirmative); COG0527 LysC aspartokinases; Belongs to the aspartokinase family.
  
  
 0.489
putA
1-pyrroline-5-carboxylate dehydrogenase (putA); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.463
putA-2
1-pyrroline-5-carboxylate dehydrogenase (putA); N-terminal end of AMF_435 (putA); psort: bacterial cytoplasm --- Certainty= 0.539(Affirmative); COG1012 PutA NAD-dependent aldehyde dehydrogenase.
     
 0.463
thiO
Thiamine biosynthesis oxidoreductase (thiO); Psort: bacterial periplasmic space --- Certainty= 0.711(Affirmative); COG0665 DadA Glycine/D-amino acid oxidases (deaminating).
     
 0.452
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (ispE); Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
      
 0.426
tmk
Thymidylate kinase (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
      
 0.412
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthetase (IspF); Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
      
 0.412
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (murA); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
      
 0.410
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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