STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
barAHistidine kinase sensor protein (barA); Psort: bacterial inner membrane --- Certainty= 0.582(Affirmative); COG0642 BaeS signal transduction histidine kinase. (474 aa)    
Predicted Functional Partners:
AMF_349
Psort: bacterial cytoplasm --- Certainty= 0.331(Affirmative); COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 0.998
czcR
Transcriptional activator protein (czcR); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.956
pdhB
Pyruvate dehydrogenase E1 beta subunit precursor (pdhB); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.832
cycM
Cytochrome C (cycM); Psort: bacterial inner membrane --- Certainty= 0.412(Affirmative); COG3303 NrfA formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit.
    
 
 0.815
prsA
Ribose-phosphate pyrophosphokinase (prsA); Psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative); COG0462 PrsA phosphoribosylpyrophosphate synthetase.
    
 0.808
fadB
3-hydroxyacyl-COA dehydrogenase bO272.3 (fadB); Psort: bacterial inner membrane --- Certainty= 0.005(Affirmative); COG1250 FadB 3-hydroxyacyl-CoA dehydrogenase.
   
   0.789
sucB
Dihydrolipoamide acetyltransferase component (sucB); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0508 AceF dihydrolipoamide acyltransferases.
    
  0.776
pdhC
Dihydrolipoamide acetyltransferase component (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
  0.776
pdhD
Dihydrolipoamide dehydrogenase (pdhD); Psort: bacterial inner membrane --- Certainty= 0.117(Affirmative).
   
  0.692
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes.
   
  0.692
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.