STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smfDNA processing protein, chain A dprA (smf); Psort: bacterial cytoplasm --- Certainty= 0.158(Affirmative); COG0758 Smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (377 aa)    
Predicted Functional Partners:
comF
Competence protein F (comF); Psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG1040 ComFC Predicted amidophosphoribosyltransferases.
 
 
 0.870
AMF_669
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.535(Affirmative); COG0658 Predicted multitransmembrane, metal-binding protein.
 
  
 0.815
AMF_468
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0606 Predicted ATPase with chaperone activity.
 
 0.784
topA
DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
   
 0.720
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.654
ssb
Single-strand binding protein (ssb); Psort: bacterial cytoplasm --- Certainty= 0.082(Affirmative); COG0629 Ssb single-stranded DNA-binding protein.
  
  
 0.562
radC
DNA repair protein (radC); Psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG2003 RadC DNA repair proteins; Belongs to the UPF0758 family.
  
  
 0.553
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.438
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.