Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
proP-2Proline/betaine transporter (proP); High sequence identity to AMF_303 and AMF_309 Higher sequence similarity to other Anaplasmataceae than AMF_303, lower than AMF_309; psort: bacterial inner membrane --- Certainty= 0.554(Affirmative); COG0477 ProP Permeases of the major facilitator superfamily. (430 aa)    
Predicted Functional Partners:
proP
Proline/betaine transporter (proP); High sequence identity to AMF_304 and AMF_309 psort: bacterial inner membrane --- Certainty= 0.518(Affirmative); COG0477 ProP Permeases of the major facilitator superfamily.
 
    
0.499
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.480
aprE
Alkaline protease secretion protein (aprE); Psort: bacterial inner membrane --- Certainty= 0.569(Affirmative); COG1404 aprE subtilisin-like serine proteases.
  
 
 0.432
AMF_342
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
      
 0.426
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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