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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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fab1Enoyl-[acyl-carrier-protein] reductase (fab1); Psort: bacterial cytoplasm --- Certainty= 0.069(Affirmative); COG0623 FabI enoyl-[acyl-carrier-protein] reductase (NADH). (282 aa)    
Predicted Functional Partners:
fabB
3-oxoacyl-(acyl-carrier-protein) synthase II (fabB); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.992
fabD
Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase.
  
 
 0.991
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase (fabZ); Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.960
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.932
fabG
3-oxoacyl-reductase (fabG); Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.920
fabK
Enoyl-(acyl-carrier-protein) reductase II; Psort: bacterial cytoplasm --- Certainty= 0.022(Affirmative).
    
 0.913
lipB
Lipoate-protein ligase B (lipB); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
     
  0.800
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III (fabH); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.785
dnaA
Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
     
 0.662
kefB
Glutathione-regulated potassium-efflux system protein KEFB (kefB); Psort: bacterial inner membrane --- Certainty= 0.637(Affirmative); COG0475 KefB Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.594
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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