Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pssACDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Psort: bacterial inner membrane --- Certainty= 0.469(Affirmative); COG1183 PssA phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (280 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase proenzyme (psd); Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 0.996
cdsA
Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.
    
 0.953
pgsA
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); Psort: bacterial inner membrane --- Certainty= 0.359(Affirmative); COG0558 PgsA phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.952
glyA
Glycine/serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
yidC
60kD inner-membrane protein (yidC); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
       0.563
ribH
Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
       0.549
nusB
N utilization substance protein B (nusB); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.541
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC); Psort: bacterial inner membrane --- Certainty= 0.385(Affirmative); COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase.
      
 0.489
uvrA
Excinuclease ABC subunit A (uvrA); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.473
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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