STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMF_349Psort: bacterial cytoplasm --- Certainty= 0.331(Affirmative); COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (455 aa)    
Predicted Functional Partners:
barA
Histidine kinase sensor protein (barA); Psort: bacterial inner membrane --- Certainty= 0.582(Affirmative); COG0642 BaeS signal transduction histidine kinase.
 0.998
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
 
 0.904
AMF_224
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.559(Affirmative); COG2202 PAS/PAC domain.
  
 
 0.714
AMF_350
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative).
       0.595
AMF_351
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.013(Affirmative).
       0.479
gdh
NAD-specific glutamate dehydrogenase; Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase.
       0.479
czcR
Transcriptional activator protein (czcR); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
0.468
dksA
dnaK suppressor protein (dksA); Psort: bacterial cytoplasm --- Certainty= 0.549(Affirmative); COG1734 DksA DnaK suppressor protein.
      
 0.428
trpS
tryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.426
hisS
Histidyl tRNA synthetase (hisS); Psort: bacterial cytoplasm --- Certainty= 0.492(Affirmative); COG0124 hisS histidyl-tRNA synthetase.
      
 0.425
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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