STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMF_349Psort: bacterial cytoplasm --- Certainty= 0.331(Affirmative); COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (455 aa)    
Predicted Functional Partners:
barA
Histidine kinase sensor protein (barA); Psort: bacterial inner membrane --- Certainty= 0.582(Affirmative); COG0642 BaeS signal transduction histidine kinase.
 0.998
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
 
 0.895
AMF_224
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.559(Affirmative); COG2202 PAS/PAC domain.
  
 
 0.699
AMF_350
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative).
       0.553
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.536
AMF_351
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.013(Affirmative).
       0.526
gdh
NAD-specific glutamate dehydrogenase; Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase.
       0.526
ntrY
Nitrogen regulation protein (ntrY); Psort: bacterial inner membrane --- Certainty= 0.567(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.998 Max cleavage site probability: 0.704 between pos. 32 and 33; COG0347 GlnK nitrogen regulatory protein PII.
 
   
 0.490
AMF_749
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.334(Affirmative).
  
  
 0.472
typA
GTP-binding protein TypA (typA); Psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG1217 TypA predicted membrane GTPase involved in stress response.
      
 0.444
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.