STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)    
Predicted Functional Partners:
coaX
Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
 
  
 0.972
coaE
dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.950
AMF_032
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0742 N6-adenine-specific methylase.
 
  
 0.783
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.614
pth
peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
   
 0.542
dcd
Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP.
   
    0.540
eno
Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.528
folC
Folylpolyglutamate synthase (folC); Psort: bacterial inner membrane --- Certainty= 0.095(Affirmative); COG0285 FolC folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
   
 0.522
ruvB
Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
  
 0.497
ribF
Riboflavin kinase / FAD synthetase protein (ribF); Psort: bacterial cytoplasm --- Certainty= 0.105(Affirmative); COG0196 RibF FAD synthase; Belongs to the ribF family.
 
   
 0.490
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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