| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF_032 | coaD | AMF_032 | AMF_379 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0742 N6-adenine-specific methylase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.783 |
| coaD | AMF_032 | AMF_379 | AMF_032 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0742 N6-adenine-specific methylase. | 0.783 |
| coaD | coaE | AMF_379 | AMF_321 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.950 |
| coaD | coaX | AMF_379 | AMF_201 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.972 |
| coaD | dcd | AMF_379 | AMF_107 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | 0.540 |
| coaD | eno | AMF_379 | AMF_448 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.528 |
| coaD | folC | AMF_379 | AMF_522 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Folylpolyglutamate synthase (folC); Psort: bacterial inner membrane --- Certainty= 0.095(Affirmative); COG0285 FolC folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.522 |
| coaD | guaA | AMF_379 | AMF_897 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP. | 0.614 |
| coaD | pth | AMF_379 | AMF_1015 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | peptidyl-tRNA hydrolase (pth); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.542 |
| coaD | ribF | AMF_379 | AMF_817 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin kinase / FAD synthetase protein (ribF); Psort: bacterial cytoplasm --- Certainty= 0.105(Affirmative); COG0196 RibF FAD synthase; Belongs to the ribF family. | 0.490 |
| coaD | ruvB | AMF_379 | AMF_129 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.497 |
| coaE | coaD | AMF_321 | AMF_379 | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.950 |
| coaE | coaX | AMF_321 | AMF_201 | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.479 |
| coaE | folC | AMF_321 | AMF_522 | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Folylpolyglutamate synthase (folC); Psort: bacterial inner membrane --- Certainty= 0.095(Affirmative); COG0285 FolC folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.421 |
| coaE | guaA | AMF_321 | AMF_897 | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP. | 0.447 |
| coaX | coaD | AMF_201 | AMF_379 | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.972 |
| coaX | coaE | AMF_201 | AMF_321 | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | dephospho-CoA kinase (coaE); Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.479 |
| coaX | eno | AMF_201 | AMF_448 | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.591 |
| dcd | coaD | AMF_107 | AMF_379 | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.540 |
| dcd | guaA | AMF_107 | AMF_897 | Deoxycytidine triphosphate deaminase (dcd); Catalyzes the deamination of dCTP to dUTP. | GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP. | 0.598 |