STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aatAAspartate aminotransferase A (aatA); Psort: bacterial cytoplasm --- Certainty= 0.178(Affirmative); COG0075 - serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (422 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.948
metC
Cystathionine beta-lyase; Psort: bacterial inner membrane --- Certainty= 0.236(Affirmative); COG0626 cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.946
putA
1-pyrroline-5-carboxylate dehydrogenase (putA); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.944
gltA
Citrate synthase (gltA); Psort: bacterial cytoplasm --- Certainty= 0.043(Affirmative); COG0372 GltA citrate synthase.
  
 0.929
purA-2
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.910
pyrB
Aspartate carbamoyltransferase pyrB (pyrB); Psort: bacterial inner membrane --- Certainty= 0.119(Affirmative); COG0540 PyrB aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
    
  0.906
gdh
NAD-specific glutamate dehydrogenase; Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase.
     
  0.900
lysC
Aspartokinase (lysC); Psort: bacterial inner membrane --- Certainty= 0.183(Affirmative); COG0527 LysC aspartokinases; Belongs to the aspartokinase family.
  
 0.900
dfp-2
Phosphopantothenoylcysteine synthase/decarboxylase (dfp); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0452 Dfp Phosphopantothenoylcysteine synthetase/decarboxylase.
  
  0.866
icd
Isocitrate dehydrogenase (icd); Psort: bacterial cytoplasm --- Certainty= 0.104(Affirmative); COG0538 Icd isocitrate dehydrogenases.
  
 
 0.831
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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