STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiBRibose 5-phosphate isomerase (RpiB); Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0698 ribose 5-phosphate isomerase. (146 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase (rpe); Psort: bacterial inner membrane --- Certainty= 0.126(Affirmative); COG0036 Rpe pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.948
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.946
prsA
Ribose-phosphate pyrophosphokinase (prsA); Psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative); COG0462 PrsA phosphoribosylpyrophosphate synthetase.
  
 
 0.942
glyA
Glycine/serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
  
 0.941
ubiG-2
3-demethylubiquinone-9 3-methyltransferase (UBIG); O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
      0.782
ubiG
3-demethylubiquinone-9 3-methyltransferase (UBIG); O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
      0.659
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
     
 0.608
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.595
AMF_424
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.197(Affirmative).
       0.523
tpiA
Triosephosphate isomerase (tpiA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0149 TpiA triosephosphate isomerase.
     
 0.505
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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