STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
putA1-pyrroline-5-carboxylate dehydrogenase (putA); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1047 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase (glnA); Psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
   
 
 0.961
glnA-2
Glutamine synthetase (glnA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
   
 
 0.961
aatA
Aspartate aminotransferase A (aatA); Psort: bacterial cytoplasm --- Certainty= 0.178(Affirmative); COG0075 - serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
   
 
 0.944
gdh
NAD-specific glutamate dehydrogenase; Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase.
  
  
 0.913
purQ
Phosphoribosylformylglycinamidine synthase I (purQ); Psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
     
  0.900
gltX
Glutamate tRNA ligase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
    
  0.818
gltX2
glutamyl-tRNA synthetase (gltX2); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
    
  0.818
pdhD
Dihydrolipoamide dehydrogenase (pdhD); Psort: bacterial inner membrane --- Certainty= 0.117(Affirmative).
   
 
 0.804
lpdA
Dihydrolipoamide dehydrogenase (lpdA); Psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes.
   
 
 0.804
gshA
Glutamate-cysteine ligase (gshA); Psort: bacterial cytoplasm --- Certainty= 0.336(Affirmative); COG2918 GshA Gamma-glutamylcysteine synthetase.
     
  0.800
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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