Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
putA-21-pyrroline-5-carboxylate dehydrogenase (putA); N-terminal end of AMF_435 (putA); psort: bacterial cytoplasm --- Certainty= 0.539(Affirmative); COG1012 PutA NAD-dependent aldehyde dehydrogenase. (110 aa)    
Predicted Functional Partners:
pdxJ
Pyridoxal phosphate biosynthetic protein (pdxJ); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
      
 0.562
ntrX
Nitrogen assimilation regulatory protein (ntrX); Psort: bacterial cytoplasm --- Certainty= 0.262(Affirmative); COG3852 NtrB signal transduction histidine kinase, nitrogen specific.
      
 0.541
thiC
Thiamin biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
      
 0.520
glnA
Glutamine synthetase (glnA); Psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
   
  
 0.511
glnA-2
Glutamine synthetase (glnA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
   
  
 0.511
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.507
dapE
Succinyl-diaminopimelate desuccinylase (dapE); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
   
 
 0.467
dhkA
Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase.
  
  
 0.464
aroA
3-phosphoshikimate 1-carboxyvinyltransferase (aroA); Psort: bacterial inner membrane --- Certainty= 0.257(Affirmative); COG0128 AroA 5-enolpyruvylshikimate-3-phosphate synthase.
     
 0.463
gltA
Citrate synthase (gltA); Psort: bacterial cytoplasm --- Certainty= 0.043(Affirmative); COG0372 GltA citrate synthase.
   
  
 0.457
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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