Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mraWS-adenosyl-methyltransferase (mraW); Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (291 aa)    
Predicted Functional Partners:
truA
tRNA pseudouridylate synthase A (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
 
 0.840
AMF_451
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.266(Affirmative).
       0.816
purA
Adenylosuccinate synthetase (purA); C-terminal end of the full-length purA; psort: bacterial cytoplasm --- Certainty= 0.325(Affirmative); COG0104 PurA Adenylosuccinate synthase.
       0.773
rpsL
30S ribosomal protein S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.
   
 
 0.722
rpsO
30S ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
    
 
 0.719
ftsA
Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.699
rpsI
30S ribosomal protein S9 (rpsI); Psort: bacterial cytoplasm --- Certainty= 0.329(Affirmative); COG0103 RpsI ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.691
pbpA2
Penicillin-binding protein (pbpA2); Psort: bacterial inner membrane --- Certainty= 0.516(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2.
  
  
 0.689
rpsB
30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 
 0.683
rpsP
30S ribosomal protein S16 (rpsP); Psort: bacterial cytoplasm --- Certainty= 0.288(Affirmative); COG0228 RpsP ribosomal protein S16.
   
 
 0.672
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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