Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxB2Thioredoxin reductase (trxB2); Psort: bacterial inner membrane --- Certainty= 0.170(Affirmative); COG0492 TrxB thioredoxin reductase. (340 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase (trxB); Psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative); COG0492 TrxB thioredoxin reductase.
  
  
  0.915
trxA
Thioredoxin (trxA); Posrt: bacterial cytoplasm --- Certainty= 0.097(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.838
tdpX1
Thioredoxin peroxidase 1 (tdpX1); Psort: bacterial cytoplasm --- Certainty= 0.065(Affirmative); COG0450 AhpC peroxiredoxin.
  
 
 0.818
adx1
Ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 (adx1); Psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0633 Fdx ferredoxin.
   
 
 0.692
atpG
ATP synthase gamma chain (atpG); Psort: bacterial cytoplasm --- Certainty= 0.154(Affirmative); COG0224 AtpG F0F1-type ATP synthase gamma subunit.
  
  
 0.602
dsbE
Thiol:disulfide interchange protein (dsbE); Psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins.
   
 
 0.565
AMF_357
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 
 0.565
pmbA
pmbA protein (pmbA); Psort: bacterial cytoplasm --- Certainty= 0.121(Affirmative); COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs.
  
    0.564
thiF
Thiamine biosynthesis protein (thiF); Psort: bacterial outside --- Certainty= 0.300(Affirmative); COG0476 ThiF dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
    0.563
folE
GTP cyclohydrolase I (folE); Psort: bacterial inner membrane --- Certainty= 0.174(Affirmative); COG0302 FolE GTP cyclohydrolase I; Belongs to the GTP cyclohydrolase I family.
  
    0.563
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.