| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF_867 | clpA | AMF_867 | AMF_538 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.666 |
| AMF_867 | groEL | AMF_867 | AMF_725 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.862 |
| AMF_867 | groES | AMF_867 | AMF_724 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | 10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.690 |
| AMF_867 | grpE | AMF_867 | AMF_012 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | GrpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.920 |
| AMF_867 | hscA | AMF_867 | AMF_485 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | Heat shock protein (hscA); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.914 |
| AMF_867 | htpG | AMF_867 | AMF_276 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | Heat shock protein (htpG); Molecular chaperone. Has ATPase activity. | 0.940 |
| AMF_867 | nifS-2 | AMF_867 | AMF_490 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | Putative cystine defulfurase (nifS-like protein); Duplicated gene; Similar to AMF_489; psort: bacterial inner membrane --- Certainty= 0.119(Affirmative); COG1104 cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.553 |
| AMF_867 | nifU | AMF_867 | AMF_488 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | Iron-sulfur cofactor synthesis protein (nifU); A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.483 |
| clpA | AMF_867 | AMF_538 | AMF_867 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative). | 0.666 |
| clpA | dnaJ | AMF_538 | AMF_978 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.798 |
| clpA | groEL | AMF_538 | AMF_725 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.479 |
| clpA | groES | AMF_538 | AMF_724 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.554 |
| clpA | grpE | AMF_538 | AMF_012 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | GrpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.827 |
| clpA | hscA | AMF_538 | AMF_485 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein (hscA); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.903 |
| clpA | htpG | AMF_538 | AMF_276 | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein (htpG); Molecular chaperone. Has ATPase activity. | 0.814 |
| dnaJ | clpA | AMF_978 | AMF_538 | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | ATP-dependent clp protease ATP-binding subunit (clpA); Psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.798 |
| dnaJ | groEL | AMF_978 | AMF_725 | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.947 |
| dnaJ | groES | AMF_978 | AMF_724 | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.868 |
| dnaJ | grpE | AMF_978 | AMF_012 | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | GrpE protein (grpE); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.982 |
| dnaJ | hscA | AMF_978 | AMF_485 | DNAJ protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | Heat shock protein (hscA); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.988 |
