STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAtRNA pseudouridylate synthase A (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (247 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.890
pyrB
Aspartate carbamoyltransferase pyrB (pyrB); Psort: bacterial inner membrane --- Certainty= 0.119(Affirmative); COG0540 PyrB aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
    0.828
rplQ
50S ribosomal protein L17 (rplQ); Psort: bacterial cytoplasm --- Certainty= 0.046(Affirmative); COG0203 RplQ ribosomal protein L17.
  
  
 0.828
truB
tRNA pseudouridine 55 synthase (truB); Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.746
mraW
S-adenosyl-methyltransferase (mraW); Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
 
 
 0.659
rpoC
DNA-directed RNA polymerase beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.610
thiD
Phosphomethylpyrimidine kinase (thiD); Psort: bacterial inner membrane --- Certainty= 0.206(Affirmative); COG0351 ThiD hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
  
    0.605
miaA
tRNA isopentenylpyrophosphate transferase (miaA); Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
 
 0.603
prfB
Peptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
 
 
 0.600
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.593
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.