Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prfBPeptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (338 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
  0.976
rpsG
30S ribosomal protein S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.952
rpsP
30S ribosomal protein S16 (rpsP); Psort: bacterial cytoplasm --- Certainty= 0.288(Affirmative); COG0228 RpsP ribosomal protein S16.
  
 
 0.945
rpmA
50S ribosomal protein L27 (rpmA); Psort: bacterial cytoplasm --- Certainty= 0.450(Affirmative); COG0211 RpmA ribosomal protein L27.
   
 
 0.939
rpsL
30S ribosomal protein S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.
   
 
 0.934
rpsF
30S ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
  
 
 0.928
rplT
Cyanelle 50S ribosomal protein L20 (rplT); Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 0.920
rpmG
50S ribosomal protein L33 (rpmG); Psort: bacterial cytoplasm --- Certainty= 0.132(Affirmative); COG0267 RpmG ribosomal protein L33.
  
 
 0.916
rpmF
Large subunit ribosomal protein L32 (rpmF); Psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative); COG0333 RpmF ribosomal protein L32.
   
 0.915
rpmB
50S ribosomal protein L28 (rpmB); Psort: bacterial inner membrane --- Certainty= 0.232(Affirmative); COG0227 RpmB ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.915
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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