STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfBPeptide chain release factor 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (338 aa)    
Predicted Functional Partners:
rpmA
50S ribosomal protein L27 (rpmA); Psort: bacterial cytoplasm --- Certainty= 0.450(Affirmative); COG0211 RpmA ribosomal protein L27.
   
 
 0.994
rplU
50S ribosomal protein L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.993
rplS
50S ribosomal subunit L19 (rplS); This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.986
rpmG
50S ribosomal protein L33 (rpmG); Psort: bacterial cytoplasm --- Certainty= 0.132(Affirmative); COG0267 RpmG ribosomal protein L33.
  
 
 0.981
rpsP
30S ribosomal protein S16 (rpsP); Psort: bacterial cytoplasm --- Certainty= 0.288(Affirmative); COG0228 RpsP ribosomal protein S16.
  
   0.978
rpsG
30S ribosomal protein S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.978
rpsF
30S ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
  
 
 0.974
rplM
50S ribosomal protein L13 (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.973
rpsL
30S ribosomal protein S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.
   
 
 0.972
rplD
50S ribosomal protein L4 (rplD); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 
 0.971
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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