STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ankAAnkyrin (ankA); Psort: bacterial cytoplasm --- Certainty= 0.332(Affirmative); COG0666 Arp ankyrin repeat proteins. (1388 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.725
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.715
msp4
Major surface protein 4 (msp4); Member of msp2 superfamily; psort: bacterial cytoplasm --- Certainty= 0.211(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.933 between pos. 29 and 30.
      
 0.659
petB
Cytochrome B (petB); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
   0.648
dnaK
DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.632
virD4
VirD4 protein (virD4); Psort: bacterial inner membrane --- Certainty= 0.355(Affirmative); COG3505 VirD4 type IV secretory pathway, VirD4 components.
      
 0.621
AMF_181
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.727(Affirmative).
    
 
 0.610
trpS
tryptophanyl-tRNA synthetase (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 
 0.601
pheS
Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit.
    
 
 0.600
sucA
2-oxoglutarate dehydrogenase E1 component (sucA); Psort: bacterial cytoplasm --- Certainty= 0.276(Affirmative); COG0567 SucA pyruvate and 2-oxoglutarate dehydrogenases, E1 component.
    
 
 0.589
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.