Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pccBpropionyl-COA carboxylase beta chain precursor (pccB); Psort: bacterial inner membrane --- Certainty= 0.042(Affirmative); COG0825 AccA Acetyl-CoA carboxylase alpha subunit. (515 aa)    
Predicted Functional Partners:
pycA
propionyl-CoA carboxylase alpha chain precursor (pycA); Psort: bacterial membrane --- Certainty= 0.771(Affirmative); COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit.
 
 0.999
birA
biotin-(acetyl-CoA carboxylase) (birA); Psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase.
  
 
 0.824
fadB
3-hydroxyacyl-COA dehydrogenase bO272.3 (fadB); Psort: bacterial inner membrane --- Certainty= 0.005(Affirmative); COG1250 FadB 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.624
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.597
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
  
 
 0.575
gltA
Citrate synthase (gltA); Psort: bacterial cytoplasm --- Certainty= 0.043(Affirmative); COG0372 GltA citrate synthase.
  
 
 0.498
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
 0.496
fabB
3-oxoacyl-(acyl-carrier-protein) synthase II (fabB); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.441
fpg
formamidopyrimidine-DNA glycosylase (fpg); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.424
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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