STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pccBpropionyl-COA carboxylase beta chain precursor (pccB); Psort: bacterial inner membrane --- Certainty= 0.042(Affirmative); COG0825 AccA Acetyl-CoA carboxylase alpha subunit. (515 aa)    
Predicted Functional Partners:
pycA
propionyl-CoA carboxylase alpha chain precursor (pycA); Psort: bacterial membrane --- Certainty= 0.771(Affirmative); COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit.
 
 0.999
birA
biotin-(acetyl-CoA carboxylase) (birA); Psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase.
  
 
 0.942
hflK-2
hflK protein; HflC and HflK could encode or regulate a protease.
    
 
 0.766
yibO
2,3-bisphosphoglycerate-independent phosphoglycerol mutase (yibO); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
      
 0.741
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.619
pheS
Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit.
      
 0.613
hflK
HFLK protein (hflK); Psort: bacterial inner membrane --- Certainty= 0.397(Affirmative); COG0330 HflC membrane protease subunits, stomatin/prohibitin homologs.
    
 
 0.594
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
  
 0.576
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
  
  
 0.569
grxC2
Glutaredoxin-like protein GRLA (grxC2); Psort: bacterial cytoplasm --- Certainty= 0.297(Affirmative); Belongs to the glutaredoxin family. Monothiol subfamily.
      
 0.551
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.