STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pstAPhosphate ABC transporter (pstA); Psort: bacterial inner membrane --- Certainty= 0.660(Affirmative); COG0581 PstA ABC-type phosphate transport system, permease component. (487 aa)    
Predicted Functional Partners:
pstS
Phosphate ABC transporter, periplasmic phosphate-binding protein; Psort: bacterial outer membrane --- Certainty= 0.239(Affirmative) bacterial periplasmic space --- Certainty= 0.239(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.984 Max cleavage site probability: 0.934 between pos. 20 and 21; COG0226 ABC-type phosphate transport system, periplasmic component.
 
 
 0.999
pstB
Phosphate ABC transporter (pstB); Psort: bacterial cytoplasm --- Certainty= 0.075(Affirmative); COG1117 PstB ABC-type phosphate transport system, ATPase component; Belongs to the ABC transporter superfamily.
 
 
 0.999
pstC
ABC-type phosphate transport system, permease component (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
0.997
sodB
Fe superoxide dismutase (sodB); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.623
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
     
 0.583
pheT
phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit.
     
 0.571
phnL
ATP transporter ATP-binding protein (phnL); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
      
 0.489
guaB
Inosine monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.461
czcR
Transcriptional activator protein (czcR); Psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
     
 0.441
virB6
VirB6; Psort: bacterial inner membrane --- Certainty= 0.626(Affirmative); COG3704 VirB6 type IV secretory pathway, VirB6 components.
       0.418
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.