era protein (Anaplasma marginale) - STRING interaction network

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era

GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (297 aa)

Predicted Functional Partners:

rpsG

0.915

rpsP

0.898

rpsI

0.896

rpsF

0.893

rpsN

0.879

rpsO

0.878

rpsJ

0.875

rpsL

0.874

rpsE

0.865

rpsB

0.861

Your Current Organism:

Anaplasma marginale

NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
era	rpsB	AMF_625	AMF_587	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.861
era	rpsE	AMF_625	AMF_679	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S5 (rpsE); With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.865
era	rpsF	AMF_625	AMF_119	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.	0.893
era	rpsG	AMF_625	AMF_183	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.915
era	rpsI	AMF_625	AMF_778	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S9 (rpsI); Psort: bacterial cytoplasm --- Certainty= 0.329(Affirmative); COG0103 RpsI ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.896
era	rpsJ	AMF_625	AMF_697	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.875
era	rpsL	AMF_625	AMF_182	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.	0.874
era	rpsN	AMF_625	AMF_683	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Small ribosomal protein S14 (rpsN); Psort: bacterial cytoplasm --- Certainty= 0.248(Affirmative); COG0199 RpsN ribosomal protein S14.	0.879
era	rpsO	AMF_625	AMF_390	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.878
era	rpsP	AMF_625	AMF_037	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S16 (rpsP); Psort: bacterial cytoplasm --- Certainty= 0.288(Affirmative); COG0228 RpsP ribosomal protein S16.	0.898
rpsB	era	AMF_587	AMF_625	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	GTP-binding protein ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.861
rpsB	rpsE	AMF_587	AMF_679	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S5 (rpsE); With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.997
rpsB	rpsF	AMF_587	AMF_119	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.	0.998
rpsB	rpsG	AMF_587	AMF_183	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.998
rpsB	rpsI	AMF_587	AMF_778	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S9 (rpsI); Psort: bacterial cytoplasm --- Certainty= 0.329(Affirmative); COG0103 RpsI ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999
rpsB	rpsJ	AMF_587	AMF_697	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S10 (rpsJ); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.997
rpsB	rpsL	AMF_587	AMF_182	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.	0.997
rpsB	rpsN	AMF_587	AMF_683	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	Small ribosomal protein S14 (rpsN); Psort: bacterial cytoplasm --- Certainty= 0.248(Affirmative); COG0199 RpsN ribosomal protein S14.	0.996
rpsB	rpsO	AMF_587	AMF_390	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.998
rpsB	rpsP	AMF_587	AMF_037	30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S16 (rpsP); Psort: bacterial cytoplasm --- Certainty= 0.288(Affirmative); COG0228 RpsP ribosomal protein S16.	0.997

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