| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ileS | leuS | AMF_514 | AMF_327 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.953 |
| ileS | pheS | AMF_514 | AMF_042 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | 0.577 |
| ileS | pheT | AMF_514 | AMF_670 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit. | 0.992 |
| ileS | rplO | AMF_514 | AMF_678 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 50S ribosomal protein L15 (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.403 |
| ileS | rpoB | AMF_514 | AMF_194 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.526 |
| ileS | rpsC | AMF_514 | AMF_690 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 30S ribosomal protein S3 (rpsC); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.533 |
| ileS | tyrS | AMF_514 | AMF_906 | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.721 |
| leuS | ileS | AMF_327 | AMF_514 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.953 |
| leuS | pheS | AMF_327 | AMF_042 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | 0.519 |
| leuS | pheT | AMF_327 | AMF_670 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit. | 0.988 |
| leuS | rplO | AMF_327 | AMF_678 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 50S ribosomal protein L15 (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.493 |
| leuS | rpoB | AMF_327 | AMF_194 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.797 |
| leuS | rpsB | AMF_327 | AMF_587 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 30S ribosomal protein S2 (rpsB); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0052 RpsB ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.634 |
| leuS | rpsC | AMF_327 | AMF_690 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 30S ribosomal protein S3 (rpsC); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.561 |
| leuS | tyrS | AMF_327 | AMF_906 | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.657 |
| pheS | ileS | AMF_042 | AMF_514 | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | isoleucine-tRNA ligase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.577 |
| pheS | leuS | AMF_042 | AMF_327 | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | leucyl-tRNA synthetase (leuS); Psort: bacterial cytoplasm --- Certainty= 0.485(Affirmative); COG0495 leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.519 |
| pheS | pheT | AMF_042 | AMF_670 | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit. | 0.999 |
| pheS | rplO | AMF_042 | AMF_678 | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | 50S ribosomal protein L15 (rplO); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.451 |
| pheS | rpoB | AMF_042 | AMF_194 | Phenylalanyl tRNA synthetase alpha subunit (pheS); Psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0016 PheS phenylalanyl-tRNA synthetase alpha subunit. | RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.504 |