STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppAProtease IV (sppA); Psort: bacterial inner membrane --- Certainty= 0.446(Affirmative); COG0616 SppA periplasmic serine proteases (ClpP class). (293 aa)    
Predicted Functional Partners:
rpsA
30S ribosomal protein S1 (rpsA); Psort: bacterial cytoplasm --- Certainty= 0.280(Affirmative); COG0539 RpsA ribosomal protein S1.
       0.816
cmk
Cytidylate kinase (cmk); Psort: bacterial cytoplasm --- Certainty= 0.151(Affirmative); COG0283 Cmk cytidylate kinase.
       0.631
trmH
Putative tRNA/rRNA methyltransferase TrmH; Psort: bacterial cytoplasm --- Certainty= 0.108(Affirmative); COG0566 SpoU rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.615
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (trmU); Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.457
AMF_704
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.292(Affirmative).
       0.449
AMF_703
Hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.655(Affirmative).
       0.442
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.