STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprDAlkaline protease secretion ATP-binding protein (aprD); Psort: bacterial inner membrane --- Certainty= 0.478(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component. (800 aa)    
Predicted Functional Partners:
aprE
Alkaline protease secretion protein (aprE); Psort: bacterial inner membrane --- Certainty= 0.569(Affirmative); COG1404 aprE subtilisin-like serine proteases.
  
 0.949
tolC
Outer membrane protein (tolC); Psort: bacterial inner membrane --- Certainty= 0.295(Affirmative); COG1538 TolC outer membrane protein.
 
  
 0.762
qor
Quinone oxidoreductase (qor); Psort: bacterial cytoplasm --- Certainty= 0.371(Affirmative); COG0604 Qor NADPH:quinone reductase and related Zn-dependent oxidoreductases.
       0.520
folP
Dihydropteroate synthase (folP); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.520
pstB
Phosphate ABC transporter (pstB); Psort: bacterial cytoplasm --- Certainty= 0.075(Affirmative); COG1117 PstB ABC-type phosphate transport system, ATPase component; Belongs to the ABC transporter superfamily.
 
     
0.511
hlyD
Putative secretion protein hlyD; Psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0845 AcrA Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.491
secD
Protein-export membrane protein (secD); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
      
 0.485
AMF_623
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.846(Affirmative); COG3577 Predicted aspartyl protease.
  
     0.478
AMF_293
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.020(Affirmative).
 
 
 0.477
yajC
Preprotein translocase subunit (yajC); The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
      
 0.459
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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