STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lipBLipoate-protein ligase B (lipB); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (214 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.996
acpP
Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 0.903
fabK
Enoyl-(acyl-carrier-protein) reductase II; Psort: bacterial cytoplasm --- Certainty= 0.022(Affirmative).
    
  0.805
fabB
3-oxoacyl-(acyl-carrier-protein) synthase II (fabB); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
fab1
Enoyl-[acyl-carrier-protein] reductase (fab1); Psort: bacterial cytoplasm --- Certainty= 0.069(Affirmative); COG0623 FabI enoyl-[acyl-carrier-protein] reductase (NADH).
     
  0.800
glmM
Phosphoglucosamine mutase (glmM/femD); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
       0.664
radC
DNA repair protein (radC); Psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG2003 RadC DNA repair proteins; Belongs to the UPF0758 family.
       0.541
birA
biotin-(acetyl-CoA carboxylase) (birA); Psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase.
     
 0.446
groES
10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.427
ribA
GTP cyclohydrolase II (ribA); Psort: bacterial cytoplasm --- Certainty= 0.289(Affirmative); COG0807 RibA GTP cyclohydrolase II.
    
   0.405
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.