STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (324 aa)    
Predicted Functional Partners:
dtbS
Dethiobiotin synthase (dtbS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
birA
biotin-(acetyl-CoA carboxylase) (birA); Psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase.
  
 
 0.980
bioA
Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.964
bioF
8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes.
 
  
 0.838
AMF_741
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.183(Affirmative).
       0.778
folD
Methylenetetrahydrofolate dehydrogenase (folD); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
      
 0.746
fabD
Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase.
  
  
 0.732
metK
S-adenosylmethionine synthetase (metK); Psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0192 MetK S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
      
 0.707
hemA
5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase.
 
  
 0.684
pheT
phenylalanyl-tRNA synthetase beta chain (pheT); Psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0072 PheT phenylalanyl-tRNA synthetase beta subunit.
     
 0.636
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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