| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| coq7 | ubiA | AMF_261 | AMF_658 | Ubiquinone biosynthesis protein (coq7); Psort: bacterial cytoplasm --- Certainty= 0.080(Affirmative); COG2941 CAT5 ubiquinone biosynthesis protein COQ7. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.423 |
| coq7 | ubiE | AMF_261 | AMF_761 | Ubiquinone biosynthesis protein (coq7); Psort: bacterial cytoplasm --- Certainty= 0.080(Affirmative); COG2941 CAT5 ubiquinone biosynthesis protein COQ7. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.908 |
| coq7 | ubiH | AMF_261 | AMF_974 | Ubiquinone biosynthesis protein (coq7); Psort: bacterial cytoplasm --- Certainty= 0.080(Affirmative); COG2941 CAT5 ubiquinone biosynthesis protein COQ7. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.547 |
| hemA | hemB | AMF_905 | AMF_306 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.968 |
| hemA | hemF | AMF_905 | AMF_564 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | 0.690 |
| hemA | hemH | AMF_905 | AMF_706 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.731 |
| hemA | ubiA | AMF_905 | AMF_658 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.712 |
| hemA | ubiD | AMF_905 | AMF_948 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.506 |
| hemA | ubiE | AMF_905 | AMF_761 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.758 |
| hemA | ubiH | AMF_905 | AMF_974 | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.574 |
| hemB | hemA | AMF_306 | AMF_905 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | 0.968 |
| hemB | hemF | AMF_306 | AMF_564 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | 0.753 |
| hemB | hemH | AMF_306 | AMF_706 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.752 |
| hemB | ubiA | AMF_306 | AMF_658 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.715 |
| hemB | ubiD | AMF_306 | AMF_948 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.579 |
| hemB | ubiE | AMF_306 | AMF_761 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.714 |
| hemB | ubiH | AMF_306 | AMF_974 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.571 |
| hemF | hemA | AMF_564 | AMF_905 | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | 5-c acid synthase (delta-aminolevulinate synthase) (hemA); Psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase. | 0.690 |
| hemF | hemB | AMF_564 | AMF_306 | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.753 |
| hemF | hemH | AMF_564 | AMF_706 | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.774 |