STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
glmSGlucosamine--fructose-6-phosphate aminotransferase (glmS); Psort: bacterial inner membrane --- Certainty= 0.200(Affirmative); COG0449 GlmS glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains. (608 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase (glmM/femD); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.971
carB
Carbamyl-phosphate synthase, large subunit (carB); Psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG0458 CarB carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
   
 0.956
glmU
UDP-N-acetylglucosamine pyrophosphorylase (glmU); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 0.944
purF
Amidophosphoribosyltransferase (purF); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.922
glnA
Glutamine synthetase (glnA); Psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
  
 
 0.919
glnA-2
Glutamine synthetase (glnA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
  
 
 0.919
carA
Carbamoyl-phosphate synthase, small chain (carA); Psort: bacterial inner membrane --- Certainty= 0.210(Affirmative); COG0505 CarA carbamoylphosphate synthase small subunit; Belongs to the CarA family.
    
 0.916
purQ
Phosphoribosylformylglycinamidine synthase I (purQ); Psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
    
 0.908
purD
Phosphoribosylamine-glycine ligase (purD); Psort: bacterial cytoplasm --- Certainty= 0.188(Affirmative); COG0151 PurD phosphoribosylamine-glycine ligase; Belongs to the GARS family.
     
 0.653
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
  
  
 0.621
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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