STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolCOuter membrane protein (tolC); Psort: bacterial inner membrane --- Certainty= 0.295(Affirmative); COG1538 TolC outer membrane protein. (465 aa)    
Predicted Functional Partners:
aprE
Alkaline protease secretion protein (aprE); Psort: bacterial inner membrane --- Certainty= 0.569(Affirmative); COG1404 aprE subtilisin-like serine proteases.
 
 
 0.982
hlyD
Putative secretion protein hlyD; Psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0845 AcrA Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.962
acrD
Acriflavin resistance protein D (acrD); Psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG0841 AcrB cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.924
AMF_781
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative).
       0.772
aprD
Alkaline protease secretion ATP-binding protein (aprD); Psort: bacterial inner membrane --- Certainty= 0.478(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component.
 
  
 0.762
phnL
ATP transporter ATP-binding protein (phnL); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
   
 
 0.715
rpsI
30S ribosomal protein S9 (rpsI); Psort: bacterial cytoplasm --- Certainty= 0.329(Affirmative); COG0103 RpsI ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
       0.608
rplM
50S ribosomal protein L13 (rplM); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
       0.608
AMF_860
Transcriptional regulator; Psort: bacterial cytoplasm --- Certainty= 0.191(Affirmative); COG1396 Predicted transcriptional regulators.
  
     0.566
AMF_1051
Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.235(Affirmative).
       0.564
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.