STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cox11Cytochrome c oxidase assembly protein (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. (207 aa)    
Predicted Functional Partners:
ctaB
Cytochrome c oxidase assembly factor (ctaB); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.992
coxW
Cytochrome C oxidase assembly protein (coxW); Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
 
 0.987
surf1
Surfeit locus protein 1 (surf1); Psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein.
 
 0.938
coxB
Cytochrome c oxidase subunit II (coxB); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.936
coxC
Cytochrome C oxidase, subunit III (coxC); Psort: bacterial inner membrane --- Certainty= 0.370(Affirmative); COG1845 CyoC heme/copper-type cytochrome/quinol oxidase, subunit 3.
 
  
 0.935
msp5
Major surface protein 5 (MSP5); Psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27.
 
 0.886
rnc
Ribonuclease III (rnc); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
  
 0.801
hflK-2
hflK protein; HflC and HflK could encode or regulate a protease.
  
    0.761
AMF_805
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.846(Affirmative); COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.
     
 0.727
AMF_806
Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
       0.718
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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