STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMF_837Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.917(Affirmative); COG1357 Unchacterized low-complexity proteins. (715 aa)    
Predicted Functional Partners:
gyrB2
DNA gyrase subunit B (gyrB2); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.869
AMF_021
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.234(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.646 Max cleavage site probability: 0.575 between pos. 27 and 28.
  
     0.527
pal
Peptidoglycan-associated lipoprotein precursor; Psort: bacterial inner membrane --- Certainty= 0.291(Affirmative); COG2885 OmpA Outer membrane protein and related peptidoglycan-associated (lipo)proteins.
  
 
 0.510
surf1
Surfeit locus protein 1 (surf1); Psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein.
  
    0.494
AMF_604
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); psort: bacterial inner membrane --- Certainty= 0.675(Affirmative); COG3704 Type IV secretory pathway, VirB6 components.
  
     0.465
AMF_602
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG3704 Type IV secretory pathway, VirB6 components.
  
     0.451
htpG
Heat shock protein (htpG); Molecular chaperone. Has ATPase activity.
  
 
   0.435
AMF_093
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative).
  
     0.429
AMF_603
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); bacterial inner membrane --- Certainty= 0.836(Affirmative) bacterial outer membrane --- Certainty= 0.790(Affirmative); COG3704 Type IV secretory pathway, VirB6 components.
  
     0.426
AMF_849
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative).
  
     0.414
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.