Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dksAdnaK suppressor protein (dksA); Psort: bacterial cytoplasm --- Certainty= 0.549(Affirmative); COG1734 DksA DnaK suppressor protein. (137 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase beta' chain (rpoC); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.888
rpoD
RNA polymerase sigma factor (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.829
rpoB
RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.819
rpoZ
DNA-directed RNA polymerase omega subunit (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.780
rpoH
RNA polymerase sigma-32 factor (rpoH); Psort: bacterial cytoplasm --- Certainty= 0.052(Affirmative); COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Belongs to the sigma-70 factor family.
  
 
 0.772
rpoA
DNA-directed RNA polymerase alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.729
greA
Transcription elongation factor greA (greA); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
 
 
 0.688
ntrX
Nitrogen assimilation regulatory protein (ntrX); Psort: bacterial cytoplasm --- Certainty= 0.262(Affirmative); COG3852 NtrB signal transduction histidine kinase, nitrogen specific.
 
  
 0.686
oma87
Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.650
rrf
Ribosome recycling factor (rrf); Psort: bacterial cytoplasm --- Certainty= 0.230(Affirmative); COG0233 Frr Ribosome recycling factor.
  
  
 0.646
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (16%) [HD]