STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate-cysteine ligase (gshA); Psort: bacterial cytoplasm --- Certainty= 0.336(Affirmative); COG2918 GshA Gamma-glutamylcysteine synthetase. (409 aa)    
Predicted Functional Partners:
gshB
Glutathione synthase (gshB); Psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG0189 RimK glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
 
  
 0.934
pepA
Leucyl aminopeptidase (pepA); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
secF
Protein export membrane protein secF (secF); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
  
 
 0.900
purQ
Phosphoribosylformylglycinamidine synthase I (purQ); Psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
  
 
  0.816
metC
Cystathionine beta-lyase; Psort: bacterial inner membrane --- Certainty= 0.236(Affirmative); COG0626 cystathionine beta-lyases/cystathionine gamma-synthases.
    
  0.803
glnA
Glutamine synthetase (glnA); Psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
     
  0.800
gdh
NAD-specific glutamate dehydrogenase; Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase.
     
  0.800
aatA
Aspartate aminotransferase A (aatA); Psort: bacterial cytoplasm --- Certainty= 0.178(Affirmative); COG0075 - serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
   
 
  0.800
putA
1-pyrroline-5-carboxylate dehydrogenase (putA); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
  0.800
glnA-2
Glutamine synthetase (glnA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0174 GlnA glutamine synthase; Belongs to the glutamine synthetase family.
     
  0.800
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.