Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mklRibonucleotide transport ATP-binding protein (mkl); Psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG1127 Ttg2A ABC-type exporter of toluene and related compounds, ATPase component. (239 aa)    
Predicted Functional Partners:
AMF_912
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative); COG0767 ABC-type toluene export system, permease component.
 
 0.999
AMF_055
Called by Glimmer 2; Conserved family protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.581(Affirmative); COG1463 Permease component of an ABC-transporter.
 
 0.993
AMF_849
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative).
  
 
 0.902
rpe
Ribulose-phosphate 3-epimerase (rpe); Psort: bacterial inner membrane --- Certainty= 0.126(Affirmative); COG0036 Rpe pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
       0.731
nuoA
NADH dehydrogenase I chain A (nuoA); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
   
    0.558
AMF_910
Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.310(Affirmative).
       0.545
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.540
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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