STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpeRibulose-phosphate 3-epimerase (rpe); Psort: bacterial inner membrane --- Certainty= 0.126(Affirmative); COG0036 Rpe pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (260 aa)    
Predicted Functional Partners:
tktA
Transketolase (TktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 0.982
rpiB
Ribose 5-phosphate isomerase (RpiB); Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0698 ribose 5-phosphate isomerase.
  
 
 0.943
mkl
Ribonucleotide transport ATP-binding protein (mkl); Psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG1127 Ttg2A ABC-type exporter of toluene and related compounds, ATPase component.
       0.735
AMF_912
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative); COG0767 ABC-type toluene export system, permease component.
       0.735
AMF_498
Conserved hypothetical protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.657
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.649
tpiA
Triosephosphate isomerase (tpiA); Psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0149 TpiA triosephosphate isomerase.
 
  
 0.632
guaA
GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP.
  
  
 0.599
AMF_147
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.075(Affirmative); COG0546 Predicted phosphatases.
  
  
 0.572
eno
Enolase 1 (2-phosphoglycerate dehydratase 1) (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.561
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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