Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
plsC1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC); Psort: bacterial inner membrane --- Certainty= 0.385(Affirmative); COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase. (241 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase (cdsA); COG0575 CdsA CDP-diglyceride synthetase.
    
 0.952
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
 
 0.950
gpsA
Gylcerol-3-phosphate dehydrogenase (gpsA); Psort: bacterial inner membrane --- Certainty= 0.191(Affirmative); COG0240 GpsA glycerol 3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.891
egsA
Glycerol-1-phosphate dehydrogenase (NAD(P)); Psort: bacterial inner membrane --- Certainty= 0.359(Affirmative); COG0371 GldA Glycerol dehydrogenase and related enzymes.
     
 0.812
pgsA
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); Psort: bacterial inner membrane --- Certainty= 0.359(Affirmative); COG0558 PgsA phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.610
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III (fabH); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.606
pyrD
Dihydroorotate dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
  
 0.582
rpsT
30S ribosomal protein S20 (rpsT); Binds directly to 16S ribosomal RNA.
       0.573
def-2
N-formylmethionylaminoacyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.570
groEL
60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.552
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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