| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF_342 | ubiA | AMF_342 | AMF_658 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.461 |
| AMF_342 | ubiB | AMF_342 | AMF_289 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Ubiquinone biosynthesis protein (ubiB); Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.485 |
| AMF_342 | ubiD | AMF_342 | AMF_948 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.639 |
| AMF_342 | ubiE | AMF_342 | AMF_761 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.480 |
| AMF_342 | ubiH | AMF_342 | AMF_974 | Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.492 |
| hemB | hemC | AMF_306 | AMF_523 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| hemB | hemF | AMF_306 | AMF_564 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | 0.753 |
| hemB | hemH | AMF_306 | AMF_706 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.752 |
| hemB | ubiA | AMF_306 | AMF_658 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.715 |
| hemB | ubiD | AMF_306 | AMF_948 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.579 |
| hemB | ubiE | AMF_306 | AMF_761 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.714 |
| hemB | ubiH | AMF_306 | AMF_974 | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.571 |
| hemC | hemB | AMF_523 | AMF_306 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.998 |
| hemC | hemF | AMF_523 | AMF_564 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | 0.734 |
| hemC | hemH | AMF_523 | AMF_706 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ferrochelatase (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.764 |
| hemC | ubiA | AMF_523 | AMF_658 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.688 |
| hemC | ubiD | AMF_523 | AMF_948 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.603 |
| hemC | ubiE | AMF_523 | AMF_761 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.572 |
| hemC | ubiH | AMF_523 | AMF_974 | Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.567 |
| hemF | hemB | AMF_564 | AMF_306 | Coproporphyrinogen III oxidase (hemF); Psort: bacterial cytoplasm --- Certainty= 0.612(Affirmative); COG0408 HemF coproporphyrinogen III oxidase. | Delta-aminolevulinic acid dehydratase (hemB); Psort: bacterial inner membrane --- Certainty= 0.202(Affirmative); COG0113 HemB delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.753 |