node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpX | dnaK | AMF_231 | AMF_630 | ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.671 |
clpX | ftsZ | AMF_231 | AMF_952 | ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.744 |
clpX | groEL | AMF_231 | AMF_725 | ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.636 |
clpX | recA | AMF_231 | AMF_061 | ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.455 |
dnaA | ftsZ | AMF_314 | AMF_952 | Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.773 |
dnaA | gatB | AMF_314 | AMF_312 | Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | glutamyl-tRNA amidotransferase subunit B (gatB); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.564 |
dnaA | groEL | AMF_314 | AMF_725 | Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.757 |
dnaA | recA | AMF_314 | AMF_061 | Chromosomal replication initiator protein (dnaA); Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.742 |
dnaK | clpX | AMF_630 | AMF_231 | DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.671 |
dnaK | ftsZ | AMF_630 | AMF_952 | DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.735 |
dnaK | groEL | AMF_630 | AMF_725 | DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 60 kD chaperonin (groEL); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.980 |
dnaK | recA | AMF_630 | AMF_061 | DNAK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.673 |
ftsA | ftsW | AMF_844 | AMF_972 | Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. | 0.837 |
ftsA | ftsZ | AMF_844 | AMF_952 | Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.999 |
ftsA | mreB | AMF_844 | AMF_388 | Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Rod shape-determining protein (mreB); Psort: bacterial inner membrane --- Certainty= 0.270(Affirmative); COG1077 MreB HSP70 class molecular chaperones involved in cell morphogenesis. | 0.641 |
ftsA | murG | AMF_844 | AMF_344 | Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.767 |
ftsW | ftsA | AMF_972 | AMF_844 | Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. | Cell division protein FTSA (ftsA); Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.837 |
ftsW | ftsZ | AMF_972 | AMF_952 | Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. | Cell division protein (ftsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.838 |
ftsW | mreB | AMF_972 | AMF_388 | Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. | Rod shape-determining protein (mreB); Psort: bacterial inner membrane --- Certainty= 0.270(Affirmative); COG1077 MreB HSP70 class molecular chaperones involved in cell morphogenesis. | 0.704 |
ftsW | murG | AMF_972 | AMF_344 | Cell division protein ftsW (ftsW); Psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.973 |