STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
elbBEnhancing lycopene biosynthesis protein 2; Psort: bacterial inner membrane --- Certainty= 0.289(Affirmative); COG3155 ElbB Uncharacterized sigma cross-reacting protein 27A (ES1 or KNP-I alpha protein). (218 aa)    
Predicted Functional Partners:
AMF_970
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative).
       0.732
clpB
ATP-dependent clp protease ATP-binding subunit (clpB); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
      
 0.559
htpG
Heat shock protein (htpG); Molecular chaperone. Has ATPase activity.
      
 0.551
clpP
ATP-dependent clp protease proteolytic subunit (clpP); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.535
trxB
Thioredoxin reductase (trxB); Psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative); COG0492 TrxB thioredoxin reductase.
      
 0.499
dksA
dnaK suppressor protein (dksA); Psort: bacterial cytoplasm --- Certainty= 0.549(Affirmative); COG1734 DksA DnaK suppressor protein.
      
 0.497
groES
10 KD chaperonin (groES); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
      
 0.495
hslV
Heat shock protein (hslV); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
      
 0.472
hslU
Heat shock protein (hslU); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.
      
 0.472
clpX
ATP-dependent clp protease ATP-binding subunit (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
      
 0.452
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.