STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiH2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase (ubiH); Psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (388 aa)    
Predicted Functional Partners:
ubiG
3-demethylubiquinone-9 3-methyltransferase (UBIG); O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.992
ubiG-2
3-demethylubiquinone-9 3-methyltransferase (UBIG); O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.990
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase (ubiE); Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
   
 
 0.950
coq7
Ubiquinone biosynthesis protein (coq7); Psort: bacterial cytoplasm --- Certainty= 0.080(Affirmative); COG2941 CAT5 ubiquinone biosynthesis protein COQ7.
  
 0.927
AMF_176
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.326(Affirmative).
  
 0.909
ubiB
Ubiquinone biosynthesis protein (ubiB); Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
   
 0.881
ubiA
4-hydroxybenzoate octaprenyltransferase (ubiA); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
   
 0.699
AMF_108
Called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.141(Affirmative).
  
 
 0.559
ispB
Octaprenyl-diphosphate synthase (ispB); Psort: bacterial inner membrane --- Certainty= 0.181(Affirmative); COG0142 IspA geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
   
 
 0.528
metK
S-adenosylmethionine synthetase (metK); Psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0192 MetK S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
     
 0.491
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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