STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (296 aa)    
Predicted Functional Partners:
mtnA
S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 
 0.965
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.945
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
 
 0.923
AQS88447.1
N-ethylammeline chlorohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.917
mtnK
Hypothetical protein; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
    
  0.900
AQS87373.1
6-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.836
fabG_2
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.718
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.657
AQS89254.1
Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.547
AQS87138.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.547
Your Current Organism:
Neoasaia chiangmaiensis
NCBI taxonomy Id: 320497
Other names: BCC 15763, N. chiangmaiensis, NBRC 101099, Neoasaia chiangmaiensis Yukphan et al. 2006, strain AC28
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