AQS88311.1 protein (Neoasaia chiangmaiensis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

AQS88311.1

RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (864 aa)

Predicted Functional Partners:

AQS86827.1

0.813

AQS89379.1

0.811

AQS88531.1

0.796

shc

0.794

AQS87817.1

0.771

AQS89185.1

0.753

AQS87818.1

0.725

AQS88204.1

0.679

AQS89162.1

0.675

AQS86826.1

0.658

Your Current Organism:

Neoasaia chiangmaiensis

NCBI taxonomy Id: 320497
Other names: BCC 15763, N. chiangmaiensis, NBRC 101099, Neoasaia chiangmaiensis Yukphan et al. 2006, strain AC28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQS86826.1	AQS86827.1	A0U93_01400	A0U93_01415	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.711
AQS86826.1	AQS87817.1	A0U93_01400	A0U93_07565	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.699
AQS86826.1	AQS87818.1	A0U93_01400	A0U93_07575	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
AQS86826.1	AQS88204.1	A0U93_01400	A0U93_09905	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.609
AQS86826.1	AQS88311.1	A0U93_01400	A0U93_10540	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
AQS86826.1	AQS88531.1	A0U93_01400	A0U93_11950	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
AQS86826.1	AQS89162.1	A0U93_01400	A0U93_00615	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.632
AQS86826.1	AQS89185.1	A0U93_01400	A0U93_01410	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.633
AQS86826.1	AQS89379.1	A0U93_01400	A0U93_07570	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
AQS86826.1	shc	A0U93_01400	A0U93_11945	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene-hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.682
AQS86827.1	AQS86826.1	A0U93_01415	A0U93_01400	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hopanoid biosynthesis associated radical SAM protein HpnJ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.711
AQS86827.1	AQS87817.1	A0U93_01415	A0U93_07565	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
AQS86827.1	AQS87818.1	A0U93_01415	A0U93_07575	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
AQS86827.1	AQS88204.1	A0U93_01415	A0U93_09905	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.501
AQS86827.1	AQS88311.1	A0U93_01415	A0U93_10540	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
AQS86827.1	AQS88531.1	A0U93_01415	A0U93_11950	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.792
AQS86827.1	AQS89162.1	A0U93_01415	A0U93_00615	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.513
AQS86827.1	AQS89185.1	A0U93_01415	A0U93_01410	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
AQS86827.1	AQS89379.1	A0U93_01415	A0U93_07570	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
AQS86827.1	shc	A0U93_01415	A0U93_11945	Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene-hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

17

average node degree:

3.09

avg. local clustering coefficient:

0.923

expected number of edges:

13

PPI enrichment p-value:

0.162

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006707

Cholesterol catabolic process

3 of 11

2.4

1.75

0.00053

GO:0006629

Lipid metabolic process

6 of 437

1.11

0.99

0.00055

GO:0006633

Fatty acid biosynthetic process

3 of 103

1.43

0.77

0.0220

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

3 of 29

1.98

1.22

0.0044

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

3 of 35

1.9

1.2

0.0044

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9435

Mixed, incl. GMC oxidoreductase, and Oxygen oxidoreductase covalent FAD-binding site

3 of 6

2.67

2.04

0.00018

CL:2969

Mixed, incl. DUF35 OB-fold domain, acyl-CoA-associated, and Thiolase

3 of 10

2.44

1.89

0.00030

CL:3441

ACP-like superfamily, and MbtH-like domain

3 of 55

1.7

1.09

0.0057

CL:3450

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group., and Male sterility protein

2 of 11

2.23

1.07

0.0103

CL:3430

Mixed, incl. ACP-like superfamily, and Cytochrome P450

4 of 163

1.36

0.96

0.0053

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kphy00984

Steroid degradation

3 of 17

2.21

2.0

0.00014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034081

Polyketide synthase complex

3 of 28

2.0

1.46

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0001

2Fe-2S

2 of 9

2.31

1.14

0.0076

KW-0596

Phosphopantetheine

3 of 59

1.67

1.03

0.0076

KW-0408

Iron

3 of 160

1.24

0.6

0.0449

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00975

Thioesterase domain

3 of 9

2.49

1.98

0.00021

PF05199

GMC oxidoreductase

2 of 9

2.31

0.83

0.0295

PF00111

2Fe-2S iron-sulfur cluster binding domain

2 of 11

2.23

0.83

0.0295

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001031

Thioesterase

3 of 12

2.37

1.61

0.0010

IPR006162

Phosphopantetheine attachment site

3 of 29

1.98

1.17

0.0056

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

3 of 35

1.9

1.12

0.0064

IPR007867

Glucose-methanol-choline oxidoreductase, C-terminal

2 of 9

2.31

0.88

0.0239

IPR000172

Glucose-methanol-choline oxidoreductase, N-terminal

2 of 9

2.31

0.88

0.0239

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00823

Phosphopantetheine attachment site

3 of 20

2.14

1.81

0.00031

SM00826

PKS_DH

2 of 11

2.23

1.13

0.0078

SM00825

Beta-ketoacyl synthase

2 of 12

2.19

1.13

0.0078

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

2 of 14

2.12

1.12

0.0078

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

2 of 15

2.09

1.11

0.0078

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