STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (577 aa)    
Predicted Functional Partners:
AKN62354.1
Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.986
menB
Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
 
 0.977
AKN62353.1
O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.873
AKN60825.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.861
AKN61375.1
O-succinylbenzoate-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.859
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.634
AKN62036.1
L-alanine-DL-glutamate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.611
AKN62164.1
Peptidase A26; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
       0.580
AKN62163.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
AKN60490.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.524
Your Current Organism:
Synechococcus sp. WH 8020
NCBI taxonomy Id: 32052
Other names: S. sp. WH 8020, Synechococcus WH8020, Synechococcus sp. (strain WH8020), Synechococcus sp. WH8020
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