Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKN62299.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (379 aa)    
Predicted Functional Partners:
AKN61891.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.984
AKN60112.1
NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
   
  0.965
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.954
AKN60455.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.943
pdhA
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.858
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
  0.858
AKN62173.1
Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.858
AKN60589.1
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
  0.858
AKN61115.1
Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadD family.
    
  0.774
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.656
Your Current Organism:
Synechococcus sp. WH 8020
NCBI taxonomy Id: 32052
Other names: S. sp. WH 8020, Synechococcus WH8020, Synechococcus sp. (strain WH8020), Synechococcus sp. WH8020
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.