STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF58517.1Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: yen:YE1684 putative prophage encoded two-component system histidine kinase. (774 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
 0.998
EEF59484.1
PFAM: GAF domain protein; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator.
 
 0.992
EEF60018.1
PFAM: response regulator receiver; KEGG: npu:Npun_F2686 GAF sensor hybrid histidine kinase.
  
 0.991
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.990
EEF59684.1
PFAM: response regulator receiver; KEGG: dvl:Dvul_2403 two component, sigma54 specific, Fis family transcriptional regulator.
 
 0.980
EEF57840.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: gsu:GSU2789 sensory box histidine kinase.
  
 0.977
EEF57583.1
Putative PAS/PAC sensor protein; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
  
 0.975
EEF61631.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.969
EEF58385.1
KEGG: aav:Aave_2063 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 0.969
EEF60905.1
PFAM: response regulator receiver; KEGG: npu:Npun_R2901 multi-sensor hybrid histidine kinase.
  
 0.959
Your Current Organism:
Pedosphaera parvula
NCBI taxonomy Id: 320771
Other names: P. parvula Ellin514, Pedosphaera parvula Ellin514, Pedosphaera parvula str. Ellin514, Pedosphaera parvula strain Ellin514, bacterium Ellin514
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.